IRONMAN: Alcoholic destroys company, seduces coworker, commits war crimes.

The site PostmodernBarney has a huge list of Uncomfortable Plot Summaries. Some examples:

BATMAN: Wealthy man assaults the mentally ill.
CLERKS: Aimless loser remains in dead-end job, abusive “friendship.”
GROUNDHOG DAY: Misanthropic creep exploits space/time anomaly to stalk coworker.
JURASSIC PARK: Theme park’s grand opening pushed back.
SIGNS: Jesus trumps science.
THE EXORCIST: Jesus trumps science.
THE SHINING: Wife and son keep author from finishing his novel.
The last one is a whopper. Be sure to scan through the 200 or so comments for some gems including another potshot at Bill Murray:
LOST IN TRANSLATION: Unfocused holiday trip leaves two people in yearning depression.
Even more on MetaFilter. Have any to add?